Весна пришла, а грипп не сдается

Чем страшен вирус и как от него защититься – советы специалиста

Эпидемия гриппа в России идет на спад, но, по прогнозам эпидемиологов Роспотребнадзора, специалистов из НИИ гриппа, о полной ее «капитуляции» можно говорить не раньше, чем через месяц. О том, как складывается ситуация в стране сегодня, что в принципе нужно знать о вирусах гриппа и что необходимо предпринимать во время эпидемии, рассказывает кандидат медицинских наук, заведующий НОО ФБГУ «НИИ гриппа» Минздрава России Игорь Никоноров.

 

— Игорь Юрьевич, какая ситуация с гриппом в России в настоящий момент? Эпидемия еще не закончилась?

— Мы все еще наблюдаем превышение эпидемического порога – на 4,2 процента. Это не много, на самом деле. По регионам ситуация такая: в Северо-Западном федеральном округе эпидемия продолжалась в пяти городах, значительно превышен порог эпидемии в Вологде – примерно на 48 процентов. Причем, в разных регионах болеют разные возрастные группы. В Калининграде и Великом Новгороде это дети от 7 до 14 лет, в Сыктывкаре чаще болели дети от 3 до 6 лет, а в Мурманске – подростки старше 15 лет.

— Почему в одних регионах болеют дети, а других, например, пожилые люди?

— Для ответа на этот вопрос надо посмотреть динамику заболеваемости гриппом и ОРВИ за весь период эпидемического сезона, т.е. с октября по апрель включительно. Кроме того, чаще болеют те, кто не привит от гриппа. В каждом новом сезоне картина заболеваемости может немного меняться. И сейчас, когда эпидемический сезон еще не закончился, делать какой-то общий анализ ситуации рано.

— В этом году больше гриппа А или В?

— По данным лабораторных исследований на текущий момент чаще в основном диагностируется вирус гриппа типа А(H3N2), а в последние недели — и вирус гриппа В. Эпидемия гриппа, которая вызывается вирусом А(Н3N2), обычно более длительная, чем вызываемая вирусом А(Н1N1), который вызывал заболевание гриппом в прошлом сезоне.

— Все с ужасом ждали в этом году какого-то особенно жестокого «гонконгского гриппа». Он был замечен в России?

— В феврале 2016 года ВОЗ рекомендовала в состав гриппозных вакцин штамм А/Hong Kong/4801/2014(H3N2). Место выделения вируса, на основе которого был разработан вакцинный штамм, Гонконг, напомнило о пандемии 1968 года, которая получила название «гонконгской» как места первого выделения нового в то время вируса А(H3N2). Вирусы А(H3N2), которые циркулируют сегодня — это дальние потомки вируса 1968 года и генетически не идентичны.

— Ученые ведь могут предполагать, какой вирус будет в следующем сезоне?

— Да, конечно. В Женеве недавно прошло заседание по вакцинам и штаммам, и там  приняли изменения, которые будут внесены в вакцину от гриппа на следующий сезон. 10 марта в нашем институте на Комиссии по вакцинным штаммам рассмотрены вопросы циркуляции штаммов вируса гриппа в текущем эпидемическом сезоне и даны рекомендации производителям иммунобиологических препаратов по составу вакцин на сезон 2017-2018. В состав вакцин будут включены следующие штаммы вирусов гриппа: А/Michigan/45/2015 (H1N1); А/Hong Kong/4801/2014 (H3N2); В/Brisbane/60/2008.

— А с учетом чего вносится эти изменения? Смотрят на текущее состояние с эпидемиями, со штаммами вирусов?

— Проводятся исследования в национальных центрах во всех странах, они дают данные по тем возбудителям, которые циркулируют на территории их стран, проводят анализ заболеваемости, какими возбудителями она вызвана в Южном полушарии, в Северном. И на основании этого дается прогноз и рекомендации на следующий сезон. Бывает, что появляется новый штамм вирусов гриппа уже после изменения состава вакцин — как это было, например в 2009 году.

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    Cetirizine, although less sedating, is non- dialyzable and possesses similar anti-histaminergic properties. The metabolism of Trabectedin can be decreased when combined with Sildenafil. Pediatric: The pharmacokinetics of INNOPRAN XL have not been investigated in patients younger than 18В years of age. Mannitol: (Moderate) Mannitol can potentiate the effects of other diuretics when these drugs are administered concurrently. Nintendo NX is powered by Nvidia Tegra technology». The relevance of these findings for patients receiving felopidine is unknown.

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    Copyright В© 1996, 2007 Merck Sharp & Dohme Corp. The therapeutic efficacy of Lubiprostone can be decreased when used in combination with Acetylsalicylic acid. Fibrosis or inflammation affecting the lower back, heart or lungs. The risk or severity of adverse effects can be increased when Trifluperidol is combined with Fluoxetine. The nitroglycerin passes from the adhesive surface through the skin-allowing medication to be absorbed directly into the bloodstream. Your health care provider may try a series of seizure medicines or combinations of medicines to find one that works best for you.

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    Adverse effects alleged to be caused by rosiglitazone were the subject of over 13,000 lawsuits against GSK; ] as of July 2010, GSK had agreed to settlements on more than 11,500 of these suits. The risk or severity of adverse effects can be increased when Regorafenib is combined with Atorvastatin. If serotonin syndrome is suspected, all serotonergic drugs should be discontinued and appropriate medical treatment should be implemented. It has also been used to prevent and treat race horses for exercise-induced pulmonary hemorrhage. The incidence of dizziness (10В mg/day: 2. Clinical aspects of antimicrobial resistance.

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    Last month it emerged that CITIC, a Chinese state-controlled firm, may bid for part of Mr Ponce’s controlling stake in SQM, as part of China’s bid to secure supplies of a vital raw material. It is presumed that the fungi colonized the land during the Cambrian (542–488. A: I have reviewed your question regarding the following medications; Amaryl (glimepiride), Synthroid (levothyroxine), Requip (ropinirole), Relafen (nabumetone), Wellbutrin (bupropion), Zocor (simvastatin), Klonipin (clonazepam), and Neurontin (gabapentin). If you experience any of the following symptoms of tendon rupture, stop taking levofloxacin and get emergency medical treatment: hearing or feeling a snap or pop in a tendon area, bruising after an injury to a tendon area, or inability to move or bear weight on an affected area. Please read this leaflet carefully before you start using Betoptic 0. Dosage is setted individually according to nosology, disease severity and sensitivity of the pathogen.

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    Rosiglitazone may cause other side effects. Feyer P, Seegenschmiedt MH, Steingraeber M: Granisetron in the control of radiotherapy-induced nausea and vomiting: a comparison with other antiemetic therapies. You should get a pregnancy test and follow up with your healthcare professional. There is also the problem that this drug is not meant to help raise testosterone levels, support healthy libido, reduce sexual anxiety, or delay orgasm, it only works to promote healthier blood flow. If you are diabetic, check your blood sugar levels on a regular basis while you are taking quetiapine. Vitamin E may increase the antiplatelet activities of Azelastine.

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    PROMETRIUM Capsules contain peanut oil and should never be used by patients allergic to peanuts. In patients receiving donepezil for more than 1 year several cases of syncope have been reported. Molly is unique and not easily defined. Pediatric Subjects Aged 12 to Less Than 18В Years (Cold Sores): In clinical trials for the treatment of cold sores, the adverse reactions reported by adolescent subjects receiving VALTREX 2В grams twice daily for 1В day, or VALTREX 2В grams twice daily for 1В day followed by 1В gram twice daily for 1В day (nВ =В 65, across both dosing groups), or placebo (nВ =В 30), respectively, included headache (17%, 3%) and nausea (8%, 0%). If you are using the oral liquid, shake the bottle well for at least 10 seconds before measuring each dose. Albiglutide: (Minor) Increased frequency of blood glucose monitoring may be required when clonidine is given with antidiabetic agents.

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    The risk or severity of adverse effects can be increased when Tarenflurbil is combined with Triamcinolone. Surprisingly, most of the plants in virtually all of the world’s terrestrial ecosystems rely on these relationships for their healthy growth. Reserve concomitant prescribing of tramadol hydrochloride and benzodiazepines or other CNS depressants for use in patients for whom alternative treatment options are inadequate. Archived from the original on 31 March 2012 . This dose represents approximately 1/28 the maximum recommended human dose calculated on a body surface area basis using total mg/m 2/week in rats and mg/m 2/week for a 50 kg human. Philip Cowen; Paul Harrison; Tom Burns (9 August 2012).

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    The therapeutic efficacy of Letaxaban can be decreased when used in combination with Desogestrel. If you use Imigran frequently. Aspirin has also been suggested as a component of a polypill for prevention of cardiovascular disease. In a randomized, double-blind, 2-week, parallel group study in children aged 3-15 years with JRA/JIA, the efficacy and safety of daily 2-3 mg/kg BW diclofenac was compared with acetylsalicylic acid (ASS, 50-100 mg/kg BW/d) and placebo – 15 patients in each group. Labetalol may increase the atrioventricular blocking (AV block) activities of Lacosamide. The serum concentration of Carvedilol can be increased when it is combined with Fluvoxamine.

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    Provestral and Provestrol, while Cyclo-Farlutal (or Ciclofarlutal) and Nogest-S 36] were formulations available outside of the U. Mild OHSS usually goes away on its own with bedrest and careful monitoring by a doctor. Ling, who was involved in the early development of naltrexone, told me, «Law enforcement loves the idea and that hasn’t changed. Too much reliance should not be placed on a single serum uric acid determination since, for technical reasons, estimation of uric acid may be difficult. Getting to a hospital rapidly will more likely lead to a better recovery. For best results, keep using this medicine as directed.

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    If you ever have trouble breathing, call your physician immediately. Therefore, caution should be exercised with concomitant administration of warfarin and FLOMAX capsules see Warnings and Precautions (5. The most frequently reported side effects when taking Levlen ED contraceptive pills are: breast tenderness, breast pain, abdominal pain, nausea, oedema, and headache, skin rash and itching, insomnia and depression. Denys, Damiaan; van der Wee, Nic; van Megen, Harold J. So I’m going to load up with Imodium, which sometimes doesn’t work either, and hope I don’t have an accident on the plane. Lipman Wolfe and Co».

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    Inflammation of the urethra or cervix that is not caused by gonorrhoea ( non-gonococcal urethritis or cervicitis). To help lower this risk, your doctor may prescribe a progestin for you to take with medroxyprogesterone. The metabolism of Oxybutynin can be decreased when combined with Fluvoxamine. At week 12, the olanzapine-treated group had more weight gain, a higher increase in body mass index ], and a higher proportion of patients with a BMI increase of at least 1 unit compared with the quetiapine and risperidone groups (p<=0. Unused supplies of tetracycline antibiotics should be discarded by the expiration date. The serum concentration of Valproic Acid can be increased when it is combined with Mifepristone.

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    CD44 mediates cell interaction with HA and the binding of the two functions as an important part in various physiologic events, 6] 8] such as cell aggregation, migration, proliferation and activation; cell–cell and cell–substrate adhesion; endocytosis of HA, which leads to HA catabolism in macrophages; and assembly of pericellular matrices from HA and proteoglycan. These are organic compounds containing the nitrogenous bicyclic alkaloid parent N-Methyl-8-azabicyclo. Don’t use a salt substitute, or any product that has potassium in it, while taking Avalide unless your doctor has told you to do so. People 80 years of age or older may be more likely to develop severe or serious side effects with XELODA. The serum concentration of Mevastatin can be increased when it is combined with Haloperidol. Each inhaler contains at least 120 actuations.

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    Caffeine facilitates learning in tasks in which information is presented passively; in tasks in which material is learned intentionally, caffeine has no effect. Bellissima DM Screening helps to extend the life of a flexographic printing press. Archived from the original on 24 September 2017. The risk or severity of adverse effects can be increased when Aripiprazole is combined with Dextromoramide. Over-the-counter aspirin is also used to prevent certain types of strokes. Losartan, sold under the trade name Cozaar among others, is a medication mainly used to treat high blood pressure.

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    Fetal/Neonatal Morbidity and Mortality: See WARNINGS, Pregnancy, Lisinopril, Fetal/Neonatal Morbidity and Mortality. Metoprolol may increase the hypotensive activities of Epanolol. The metabolism of Roxithromycin can be decreased when combined with Sildenafil. Both men and women taking this medicine should use birth control to prevent pregnancy. The risk or severity of adverse effects can be increased when Labetalol is combined with Etacrynic acid. Ponstel should not be administered to patients with pre-existing renal disease or in patients with significantly impaired renal function ( see WARNINGS; Renal Toxicity and Hyperkalemia) .

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    The bioavailability of Triamcinolone can be decreased when combined with Aloglutamol. Although clinical experiences have not identified differences in effectiveness and safety between the elderly (≥65 years) and younger patients, these conclusions are limited by small sample sizes for patients ≥75 years old. The risk or severity of adverse effects can be increased when Tixocortol is combined with Norfloxacin. Metronidazole has been reported to increase plasma concentrations of busulfan, which can result in an increased risk for serious busulfan toxicity. Yellow Card Scheme at: www. There is no specific antidote, and treatment is essentially symptomatic and supportive.

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    During the past decade more than 100 papers dealt with the use of AChEIs or memantine in severe AD (sAD), but only a few studies provide evidence in favor of a positive therapeutic intervention with donepezil in sAD ( Feldman et al 2001 , 2003 , 2005 ; Bullock et al 2005 ; Forchetti 2005 ; Winblad et al 2006a). Protease inhibitors are used in combination with other antiretroviral agents for the treatment of HIV infection. The metabolism of Diphenhydramine can be decreased when combined with Venlafaxine. Take Zyprexa exactly as prescribed. This medicine may be harmful if swallowed. Early human civilizations discovered that consuming plants containing caffeine offeredВ stimulating effects and these plants even were considered sacred in some cases.

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    Meptazinol may increase the serotonergic activities of Paroxetine. It provides less symptomatic relief than alpha-1 blockers such as tamsulosin and symptomatic relief is slower in onset (six months or more of treatment with finasteride may be required to determine the therapeutic results of treatment). Archived from the original on March 7, 2016 . The metabolism of Nilvadipine can be decreased when combined with Clarithromycin. UNII U3H27498KS CAS number 84057-84-1 Weight Average: 256. Medroxyprogesterone is the generic name of the drug and its INN and BAN.

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    Alcohol may worsen certain side effects of hydroxyurea. The serum concentration of Azelastine can be increased when it is combined with Vemurafenib. Generic doxycycline hyclate is covered by most Medicare and insurance plans, but manufacturer and pharmacy coupons can offset the cost. Fluoxetine may increase the antiplatelet activities of Lumiracoxib. Estradiol is not produced in the gonads only, in particular, fat cells produce active precursors to estradiol, and will continue to do so even after menopause. The risk or severity of adverse effects can be increased when Meloxicam is combined with 19-norandrostenedione.

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